Acrylic acids and derivatives
Medchemexpress LLC Bis-acrylate-PEG6 5g
Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Thiethylperazine dimaleate | 1179-69-7 | 10 MG
Thiethylperazine dimaleate is a phenothiazine derivative used as a research reagent and analytical standard. It acts as a dopamine D2 and histamine H1 receptor antagonist, and has demonstrated anti-emetic, antipsychotic, and antimicrobial activities; it has also been reported to activate ABCC1 and reduce amyloid-β load in animal studies.
- Dopamine D2 and histamine H1 receptor antagonist.
- Anti-emetic and antipsychotic activity reported in studies.
- ABCC1 activator shown to reduce amyloid-β in mice.
- Molecular weight 631.76 g/mol; CAS 1179-69-7.
- Supplied as the dimaleate salt; store sealed at 4°C, protect from moisture and light.
Medchemexpress LLC Bis-acrylate-PEG6 100mg
Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | MFCD09833218 | 99.9% | 649.70 g/mol | C32H42F3N5O6 | 10 MG
Vicriviroc maleate is the maleate salt of vicriviroc, a potent and selective CCR5 antagonist used as a research compound. It is orally bioavailable and CNS penetrant, with a reported Ki of approximately 2.5 nM and low-nanomolar antiviral activity in cell assays. Supplied as a high-purity white to off-white solid for laboratory research.
- Potent CCR5 antagonist (Ki ≈ 2.5 nM).
- Inhibits HIV-1 entry in cell assays at low nanomolar concentrations.
- High purity suitable for research use (>99.9%).
- White to off-white solid form.
- Stable when stored sealed at 4°C; protect from moisture.
- Commonly used in antiviral and chemokine receptor research.
Medchemexpress LLC Kauniolide | 81066-45-7 | MFCD28167766 | 230.30 | 1 MG
Kauniolide is a natural compound intended for research use only. This product is not for sale to patients.
- For research use only.
- Not for sale to patients.
Medchemexpress LLC Salvianolic acid E | 142998-46-7 | 5 MG
Salvianolic acid E is a natural compound isolated from Salvia miltiorrhiza. It is intended for research use only and has not been fully validated for medical applications.
- Natural compound
- Isolated from Salvia miltiorrhiza
- Intended for research applications
- Requires specific storage conditions to maintain stability
Medchemexpress LLC Dihydromethysticin | 19902-91-1 | 276.29 | 1 MG
Dihydromethysticin is an orally active natural ingredient extracted from Piper methysticum. It functions as an anti-cancer agent by inhibiting carboxylesterase 1 and CYP2A5, while also upregulating NLRC3 and inducing apoptosis. This compound has demonstrated anticancer activity against both colorectal cancer and lung adenoma.
- Inhibits carboxylesterase 1 (Ki = 68.2 μM)
- Inhibits CYP2A5
- Upregulates NLRC3 and induces apoptosis
- Exhibits anticancer activity against colorectal cancer and lung adenoma
- Suppresses proliferation, migration, and invasion of colorectal cancer cells
- Promotes G0/G1 arrest in colorectal cancer cells
- Completely inhibits lung adenoma formation
Medchemexpress LLC Skimmin (Umbelliferone glucoside) | 93-39-0 | 1 MG
Skimmin (Umbelliferone glucoside) is a pharmacologically active molecule derived from Hydrangea paniculata, known for its use in traditional Chinese medicine as an anti-inflammatory agent. It exhibits renal protective properties by improving creatinine clearance and reducing kidney injuries. Additionally, Skimmin demonstrates anti-amoebic, anti-cancer, and neuroprotective activities.
- Oral bioavailability
- Anti-inflammatory agent
- Renal protective activity
- Reduces plasma creatinine and kidney injuries
- Anti-amoebic activity against Entamoeba histolytica
- Anti-cancer activity
- Neuroprotective activity
- Reduces cardiac fibrosis
- Decreases inflammatory markers in cardiac tissues
- Potential for diabetes and related disease research
Apexbio Technology LLC Ibutilide Fumarate 122647-32-9 10mg
Ibutilide Fumarate (CAS 122647-32-9) is a small molecule classified as a Class III antiarrhythmic agent It acts primarily by enhancing slow inward sodium currents and delaying repolarization through inhibition of the rapid component of the cardiac delayed rectifier potassium current (IKr) resulting in prolongation of the cardiac action potential Ibutilide is utilized in research to investigate pharmacological cardioversion of atrial arrhythmias specifically studying the acute conversion of atrial fibrillation and atrial flutter to normal sinus rhythm Its properties make it valuable for exploring the mechanisms of antiarrhythmic therapy and cardiac electrophysiology
Medchemexpress LLC HY-70081A 5mg Medchemexpress, Sumanirole (maleate) CAS:179386-44-8 Purity:>98%
Medchemexpress, HY-70081A 5mg Sumanirole (maleate) CAS:179386-44-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-19816A 5mg Medchemexpress, Avitinib (maleate) CAS:1557268-88-8 Purity:>98%
Medchemexpress, HY-19816A 5mg Avitinib (maleate) CAS:1557268-88-8 Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor with an IC50 of 7.68 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.